You can fly directly to Vancouver, British Columbia International Airport (YVR). Then take a SkyTrain to downtown. Other nearby airports are Abbotsford, British Columbia; Bellingham Washington; and Seattle Washington but these will add considerable time to your travel. Shuttles from Abbotsford Airport to Vancouver are here. Shuttles from SeaTac and Bellingham airports to Vancouver are here. Specific directions to hotel will be on website.
